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放大字体  缩小字体    发布日期:2019-09-02  来源:仪器信息网  作者:Mr liao  浏览次数:735
核心提示:Hyaluronic acid hyaluronic MedChemExpress LLC 价格:面议 生产地:品牌:MedChemExpress (MCE) 移动电话:18019480960公司传真:86-021-53700325 更新时间:2019-06-10 MedChemExpress (MCE) 专注于为全球科学家提供高品质的生物活性小分子化合物,化合物库及各类试剂盒,总部位于美国新泽西。 MedChemExpress (MCE) 产品作用于 20 多个热门信号通路及研究领域的300多个细
Hyaluronic acid hyaluronic MedChemExpress LLC

价格:面议

生产地:品牌:MedChemExpress (MCE)

移动电话:18019480960公司传真:86-021-53700325

更新时间:2019-06-10


MedChemExpress (MCE) 专注于为全球科学家提供高品质的生物活性小分子化合物,化合物库及各类试剂盒,总部位于美国新泽西。
 MedChemExpress (MCE) 产品作用于 20 多个热门信号通路及研究领域的300多个细分靶点,拥有 10000 特异性抑制剂、激动剂,以及 30 活性化合物筛选库;
 我们坚持对所有产品进行严格质检,确保产品的高品质和高纯度;
 MedChemExpress (MCE) 产品已被全球数万名科学家信赖,并被大量Top文献和Patent引用;
 我们拥有专业的技术团队追踪全球前沿科技进展,不断丰富各个靶点的特异性产品,坚持做 您身边的抑制剂大师 ;
 MedChemExpress (MCE) 与全球众多知名药企和科研机构保持深度合作;
 大量产品有中国库存,工作日 16:00 前订单确保当日发货,次日送达。
MCE 中国:www.MedChemExpress.cn

Hotline: 400-820-3792
Tel: 021-58955995
Email: sales@MedChemExpress.cn
Tech Support: 021-58950656


Hyaluronic acid

产品活性:透明质酸是由二糖的重复单元组成的生物聚合物,应用领域广泛。

研究领域:metabolic Enzyme/Protease

作用靶点:Endogenous metabolite

In Vitro: Hyaluronic acid (HA) is widely used in aesthetic medicine due to its binding ability with a large number of water molecules. It improves tissue hydration and their resistance to mechanical damage. HA plays an important role in wound healing, ovulation, fertilization, signal transduction, and tumor physiology. HA is used in joint diseases such as osteoarthritis or rheumatoid arthritis. HA of a high molecular mass reduces the chemotaxis and migration of inflammatory cells which acts as a good barrier to the inflammatory process and protects against the effects of free radicals. HA is used in ophthalmology due to its lubricating properties for the corneal endothelium, and improves tissue hydration and cellular resistance to mechanical damage in aesthetic dermatology, and has marginal adverse effects. Several trials indicate its role in tumor markers, liver diseases, and in pharmaceuticals. Hyaluronan plays an important role in cancer growth and metastasis. HA and HA fragment-tumor cell interaction could activate the downstream signaling pathways, promoting cell proliferation, adhesion, migration and invasion, and inducing angiogenesis, lymphangiogenesis, epithelial-mesenchymal transition, stem cell-like property, and chemoradioresistance in digestive cancers.

In Vivo: The impact of applied intra-articular HA has been proven in many studies in animals. Studies on HA have shown that it promotes the synthesis of cartilage matrix, prevents its degradation, reduces inflammation, stimulates the synthesis of endogenous HA, and improves the resilience and moisture of cartilage . High molecular size HA preparations, applied topically, promote healing of fresh skin wounds. They also promote the healing of venous leg ulcers and are useful in the management of chronic wounds.

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