中文名称:精氨酸加压素受体2抗体
抗体英文名: AVPR2 Antibody
供应商:古朵生物
靶点: AVPR2
浓度: 1mg/ml
应用范围: WB: 1:100-500 E: 1:500-1000 IHC: 1:100-500 IF: 1:100-500 ICC: 1:100-500
宿主: Rabbit
适应物种: Hu, Mo, Rat, Dog, Cow, Hor, Sheep
标记物: 无标记(PLlabs可供应生物素、酶、荧光素标记的抗体)
克隆性: 否
保存条件: 保存于-20℃
形态: 液态
亚型: Rabbit Polyclonal IgG
免疫原: Peptide derived from human AVPR2.
规格: 0.1ml
Background:
AVPR2 is a receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. AVPR2 is expressed in the kidney tubule, predominantly in the distal convoluted tubule and collecting ducts. The AVPR2 receptor is also expressed outside the kidney although its tissue localization is uncertain.
Alternate Names:
arginine vasopressin receptor 2; ADHR; Antidiuretic hormone recepto; Arginine vasopressin receptor 2; AVP R2; AVPR 2; AVPR V2; DI1; DIR 3; DIR; DIR3; NDI; Nephrogenic diabetes insipidus; Renal type arginine vasopressin recepto; V2R; Vasopressin V2 receptor.
精氨酸加压素受体2抗体实验原理 性质检测:
对制备的McAb进行系统的鉴定是十分必要的。应对其做如下方面的鉴定:
抗体特异性的鉴定:除用免疫原(抗原)进行抗体的检测外,还应用与其抗原成分相关的其它抗原进行交叉试验,方法可用ELISA、IFA法。
例如:
①制备抗黑色素瘤细胞的McAb,除用黑色素瘤细胞反应外,还应用其它脏器的肿瘤细胞和正常细胞进行交叉反应,以便挑选肿瘤特异性或肿瘤相关抗原的单克隆抗体。
②制备抗重组的细胞因子的单克隆抗体,应首先考虑是否与表达菌株的蛋白有交叉反应,其次是与其它细胞因子间有无交叉。
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