美国Seracare衣原体IgG(Chlamydia IgG)
广州健仑生物科技有限公司
广州健仑长期供应各种生物原料,主要代理品牌:美国Seracare、西班牙Certest、美国Fuller等等。
主要产品包括各种标准品、阳性对照品、单克隆抗原抗体。
其中常见的有:弓形虫病、西尼罗河病毒、类风湿因子、疟疾、麻疹、莱姆病、百日咳杆菌、大肠杆菌、鼠伤寒沙门氏菌、李斯特菌等阳性对照品。
美国Seracare衣原体IgG(Chlamydia IgG)
我司还提供其它进口或国产试剂盒:登革热、疟疾、流感、A链球菌、合胞病毒、腮病毒、乙脑、寨卡、黄热病、基孔肯雅热、克锥虫病、违禁品滥用、肺炎球菌、军团菌、化妆品检测、食品安全检测等试剂盒以及日本生研细菌分型诊断血清、德国SiFin诊断血清、丹麦SSI诊断血清等产品。
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【Seracare产品介绍】
编号
英文名称
中文名称
JL-FA-01
Amebiasis (AME)
阿米巴病
JL-FA-02
Allergens, Rast scores
过敏原,放射性过敏原吸收实验。指对特定的人群引起免疫反应或者过敏反应的食品中的蛋白质
JL-FA-03
Allergens, Rast scores negative
过敏原,放射性过敏原吸收实验阴性
JL-FA-04
Anti-cyclic citrullinated peptide Antibody (CCP) Arthritis
抗环瓜氨酸肽抗体
JL-FA-05
ASCA Saccharomyces Cerevi
人抗酿酒酵母抗体(ASCA)
JL-FA-06
Aspergillis
麴菌病
JL-FA-07
Beta 2 Glycoprotein
2糖蛋白
JL-FA-08
Beta 2 Glycoprotein IgM
2糖蛋白 IGM
JL-FA-09
Bordela Pertussis
百日咳杆菌
JL-FA-10
Bordela Pertussis IgM
百日咳杆菌 IGM
JL-FA-11
C-ANCA
C-抗中性粒细胞胞浆抗体(ANCA)
JL-FA-12
Cardiolipin
心肌磷脂
JL-FA-13
Cardiolipin IgA
心肌磷脂 IGA
JL-FA-14
Cardiolipin IgG
心肌磷脂 IGG
JL-FA-15
Cardiolipin IgM
心肌磷脂 IGM
JL-FA-16
Cerebral Spinal Fluid
脑脊髓液
JL-FA-17
Chagas
恰加斯病/南美锥虫
JL-FA-18
Chlamydia
衣原体
JL-FA-19
Chlamydia IgA
衣原体IGA
JL-FA-20
Chlamydia IgG
衣原体IGG
JL-FA-21
Chlamydia IgM
衣原体IGM
JL-FA-22
Chlamydia Neg
衣原体阴性
JL-FA-23
Clotting Factor C3
凝固因子C3
JL-FA-24
Clotting Factor C4
凝固因子C4
JL-FA-25
Coccidiodes
球孢菌
JL-FA-26
Cytomegalovirus (CMV) Neg
巨细胞病毒抗体阴性
JL-FA-27
CMV IgG
巨细胞病毒 IGG阳性
JL-FA-28
CMV IgM VCA
巨细胞病毒 IGM 阳性
JL-FA-29
C-Reactive Protein (CRP)
C-反应蛋白质
JL-FA-30
Dengue Fever
登革热
JL-FA-31
Dengue Fever IgM
登革热 IGM
JL-FA-32
DS (Double Stranded) DNA
双链脱氧核糖核酸
JL-FA-33
EBNA (Epstein-Barr nuclear antigen) IgG
EB病毒核抗原 IGG
JL-FA-34
EBNA (Epstein-Barr nuclear antigen) IgM
EB病毒核抗原 IGM
JL-FA-35
Epstein Barr Virus (EBV) Negative Plasma
EB病毒阴性血浆
JL-FA-36
Epstein Barr Virus (EBV) EA IgM
EB病毒早期抗原 IGM
JL-FA-37
Epstein Barr Virus (EBV) VCA IgM
EB病毒壳蛋白 IGM
JL-FA-38
Epstein Barr Virus (EBV) EA IgG
EB病毒早期抗原 IGG
JL-FA-39
EMA (Endomysial Antibodies)
肌内膜
JL-FA-40
Gliadin
麸蛋白,麦醇溶蛋白,麦胶蛋白
JL-FA-41
Gliadin IgG
麦醇溶蛋白 IGG
JL-FA-42
Gliadin IgA
麦醇溶蛋白 IGA
JL-FA-43
Glomerular Basement Membrane (GBMA)
肾小球基底膜病
JL-FA-44
Helicobacter pylori IgA
幽门螺旋杆菌IGA
JL-FA-45
Helicobacter pylori IgG
幽门螺旋杆菌IGG
JL-FA-46
Helicobacter pylori IgM
幽门螺旋杆菌IGM
JL-FA-47
Helicobacter pylori Negative
幽门螺旋杆菌阴性
JL-FA-48
Helicobacter pylori Positive Plasma
幽门螺旋杆菌阴性血浆
JL-FA-49
Hepatitis A Virus (HAV) Pos. Plasma
甲型肝炎病毒阳性血浆
JL-FA-50
Hepatitis A Virus (HAV) IgM
甲型肝炎病毒IGM
JL-FA-51
Hepatitis B Core (HBc) IgG
乙型肝炎病毒核心 IGG
JL-FA-52
Hepatitis B Core (HBc) IgM
乙型肝炎病毒核心 IGM
JL-FA-53
Anti Hbe (Antibody to HBV antigen)
乙肝抗体
JL-FA-54
Hepatitis Delta Virus
丁型肝炎病毒
JL-FA-55
HBeAg (HBV e antigen)
乙肝 E抗原
JL-FA-56
anti-HBs (HBV surface antibody)
乙肝表面抗体
JL-FA-57
Hepatitis B (HBsAg) "Chronic"
乙型肝炎(乙肝表面抗原) 慢性病
JL-FA-58
HBsAg (HBV surface antigen) Serum
乙肝表面抗原血清
JL-FA-59
HBsAg (AD)
乙肝表面抗原(AD)
JL-FA-60
HBsAg (AY)
乙肝表面抗原(AY)
JL-FA-61
HBV Positive Plasma
乙肝阳性血浆
JL-FA-62
HBV DNA Plasma
乙肝DNA血浆
JL-FA-63
HBV DNA Serum
乙肝DNA血清
JL-FA-64
HBV DNA type A
A型 乙肝DNA
JL-FA-65
HBV DNA type B
B型 乙肝DNA
JL-FA-66
HBV DNA type C
C型 乙肝DNA
JL-FA-67
HBV DNA type D
D型 乙肝DNA
JL-FA-68
HBV DNA type E
E型 乙肝DNA
JL-FA-69
HBV DNA type F
F型 乙肝DNA
JL-FA-70
HBV Antibody HCV Antibody Plasma CO-INFECTED
乙肝和丙肝联合感染血浆
JL-FA-71
HCV (Hepatitis C Virus) Antibody
丙型肝炎抗体
JL-FA-72
HCV Core Antigen Positive
丙肝核心抗原 阳性
JL-FA-73
HCV RNA PLASMA Genotype 1
基因1型丙肝RNA 血浆
JL-FA-74
HCV RNA PLASMA Genotype 2
基因2型丙肝RNA 血浆
JL-FA-75
HCV RNA PLASMA Genotype 3
基因3型丙肝RNA 血浆
JL-FA-76
HCV RNA PLASMA Genotype 4
基因4型丙肝RNA 血浆
JL-FA-77
HCV RNA PLASMA Genotype 5
基因5型丙肝RNA 血浆
JL-FA-78
HCV RNA PLASMA Genotype 6
基因6型丙肝RNA 血浆
JL-FA-79
HCV Riba single band
丙肝免疫印迹单波段
JL-FA-80
HCV RIBA Pos. (multiple bands)
丙肝免疫印迹阳性多波段
JL-FA-81
HCV Negative
丙肝阴性
JL-FA-82
HCV RNA Pos (quantitative)
丙肝RNA阳性(定量)
JL-FA-83
Hepatitis E
戊型肝炎
JL-FA-84
Herpes Simplex Virus (HSV)1/2 Positive Plasma
单纯性疱疹病毒1/2阳性血浆
JL-FA-85
Herpes Simplex Virus (HSV) 1 Negative Plasma
单纯性疱疹病毒1 阴性血浆
JL-FA-86
Herpes Simplex Virus (HSV) 1 IgG
单纯性疱疹病毒1 IGG
JL-FA-87
Herpes Simplex Virus (HSV 1) IgM
单纯性疱疹病毒1 IGM
JL-FA-88
Herpes Simplex Virus (HSV) 2 IgG
单纯性疱疹病毒2 IGG
JL-FA-89
Herpes Simplex Virus (HSV) 2 IgM
单纯性疱疹病毒2 IGG
JL-FA-90
Histone
组蛋白
JL-FA-91
Human Anti Mouse Ab (HAMA)
人抗鼠抗体
JL-FA-92
Human immunodeficiency virus (HIV) 1 Neg
HIV I 阴性
JL-FA-93
anti Human immunodeficiency virus (HIV) 1 Plasma
抗HIV I 血浆
JL-FA-94
anti Human immunodeficiency virus (HIV) 1 Serum
抗HIV I 血清
JL-FA-95
anti Human immunodeficiency virus (HIV) 2 Western Blot Tested
抗HIV 2 免疫印迹
JL-FA-96
anti Human immunodeficiency virus (HIV) 1/2 2 HIV (+)
抗HIV 1/2 2 HIV阳性
JL-FA-97
Human immunodeficiency virus (HIV) Ag
HIV抗原
JL-FA-98
HIV RNA (quantitative) Plasma
HIV RNA 定量血浆
JL-FA-99
HIV RNA (quantitative) Serum
HIV RNA 定量血清
JL-FA-100
HIV1 Subtype A
HIV1 亚型A
JL-FA-101
HIV1 Subtype B
HIV1 亚型B
JL-FA-102
HIV1 Subtype C
HIV1 亚型C
JL-FA-103
HIV1 Subtype D
HIV1 亚型D
JL-FA-104
HIV1 Subtype E
HIV1 亚型E
JL-FA-105
HIV1 Subtype F
HIV1 亚型F
JL-FA-106
HIV1 Subtype G
HIV1 亚型G
JL-FA-107
HIV1 Subtype H
HIV1 亚型H
JL-FA-108
HIV1 Subtype J
HIV1 亚型J
JL-FA-109
HIV1 Subtype K
HIV1 亚型K
JL-FA-110
HIV1 Group O
HIV1 亚型O
JL-FA-111
Human immunodeficiency virus (HIV) 2 Antibody Plasma
HIV 2 抗体血浆
JL-FA-112
Human immunodeficiency virus (HIV) 2 Antibody Serum
HIV 2 抗体血清
JL-FA-113
HPV (Human Papiloma Virus) Negative
人乳状瘤病毒HPV阴性
JL-FA-114
HPV (Human Papiloma Virus) Positive
人乳状瘤病毒HPV阳性
JL-FA-115
Human immunodeficiency virus (HIV) Antibody HCV Antibody Plasma COINFECTED
HIV 抗体 HCV
JL-FA-116
Human T-cell Lymphotropic Virus (HTLV) I/II
人嗜T淋巴细胞病毒(HTLV) I/II
JL-FA-117
Human T-cell Lymphotropic Virus (HTLV) I
人嗜T淋巴细胞病毒(HTLV) I
JL-FA-118
Human T-cell Lymphotropic Virus (HTLV) II
人嗜T淋巴细胞病毒(HTLV) II
JL-FA-119
Jo-1
多发性肌炎抗原JO-1
JL-FA-120
IgE 5,000 Ku/L
IgE 5,000 Ku/L
JL-FA-121
Legionella
军团杆菌属
JL-FA-122
Leptospira
军团杆菌属
JL-FA-123
Lyme Disease
莱姆(氏)病:蜱传播的全身性疾病,常在夏季发生
JL-FA-124
Lyme IgG
莱姆(氏)病 IGG
JL-FA-125
Lyme IgM
莱姆(氏)病 IGM
JL-FA-126
Lyme Disease Neg
莱姆(氏)病 阴性
JL-FA-127
Malaria
疟疾
JL-FA-128
Mononucleosis (infectious)
单核细胞增多症(有传染性的)
JL-FA-129
Mononucleosis Negative
单核细胞增多症阴性
JL-FA-130
Measles Negative
麻疹 阴性
JL-FA-131
Measles IgG
麻疹 IGG
JL-FA-132
Measles IgM
麻疹 IGM
JL-FA-133
Microsomal Anti-thyroid peroxidase antibody (TPO) Positive Plasma Standard Titer (typically 1,000-3,000 IU/mL)
微粒体抗甲状腺过氧化物酶抗体
JL-FA-134
Microsomal Anti-thyroid peroxidase antibody (TPO) Negative Plasma
微粒体抗甲状腺过氧化物酶抗体
JL-FA-135
Anti-mitochondrial antibody (AMA)
抗线粒体抗体
JL-FA-136
Multiple Sclerosis
多发性硬化症
JL-FA-137
Mumps IgG
流行性腮腺炎 IGG
JL-FA-138
Mumps Ab IgM
流行性腮腺炎抗体 IGM
JL-FA-139
Mumps Antibody Negative Plasma
流行性腮腺炎抗体阴性血浆
JL-FA-140
Mumps Antibody Negative Serum
流行性腮腺炎抗体阴性血清
JL-FA-141
Myeloma Plasma
骨髓瘤血浆
JL-FA-142
Myeloma IgA
骨髓瘤IGA
JL-FA-143
Myeloma IgE
骨髓瘤IGE
JL-FA-144
Myeloma IgG
骨髓瘤IGG
JL-FA-145
Myeloma IgM
骨髓瘤IGM
JL-FA-146
Mycoplasma
支原体
JL-FA-147
Mycoplasma Negative
支原体阴性
JL-FA-148
Mycoplasma IgG
支原体IGG
JL-FA-149
Mycoplasma IgM
支原体IGM
JL-FA-150
Mycoplasma PCR
支原体PCR
JL-FA-151
Normal Human Plasma
正常人血浆
JL-FA-152
Normal Human Serum
正常人血清
JL-FA-153
Nuclear Antibody Centromere
核抗体着丝粒
JL-FA-154
Nuclear Antibody, Speckled ANA
核抗体,斑点抗核抗体
JL-FA-155
Nuclear Antibody, Nucleolar ANA
核抗体,核仁抗核抗体
JL-FA-156
Nuclear Antibody, Homogeneous ANA
核抗体,同质抗核抗体
JL-FA-157
Nuclear Antiobody, Speckled. (ANA) Negative
核抗体,斑点。抗核抗体阴性
JL-FA-158
P-ANCA (associated neutrophil cytoplasmic antibodies)
相关的嗜中性粒细胞胞浆抗体
JL-FA-159
Parietal Cell Antibody (PCA)
胃)壁细胞抗体
JL-FA-160
Parvo positive plasma
细小病毒阳性血浆
JL-FA-161
Parvo IgM
细小病毒 IGM
JL-FA-162
Parvo IgG
细小病毒 IGG
JL-FA-163
Parvo Negative Plasma
细小病毒阴性血浆
JL-FA-164
Parvo DNA positive
细小病毒 DNA 阳性
JL-FA-165
Phospholipid Positive Plasma
磷脂阳性血浆
JL-FA-166
Prothrombin
凝血酶原,凝血因子
JL-FA-167
Rheumatoid Factor (RF) 1000 IU/mL
类风湿因子 1000 IU/mL
JL-FA-168
Rheumatoid Factor (RF) 1001-2000 IU/mL
类风湿因子1001-2000 IU/mL
JL-FA-169
Rheumatoid Factor (RF) 2001-4000 IU/mL
类风湿因子 2001-4000 IU/mL
JL-FA-170
Rheumatoid Factor (RF) 4001-5000 IU/mL
类风湿因子 4001-5000 IU/mL
JL-FA-171
Rheumatoid Factor (RF) 5000 IU/mL
类风湿因子 5000 IU/mL
JL-FA-172
Ribonucleoprotein (RNP) Positive
核糖核蛋白阳性
JL-FA-173
Rubella Chimeric
风疹
JL-FA-174
Rubella Negative
风疹阴性
JL-FA-175
Rubella IgG
风疹IGG
JL-FA-176
Rubella IgM
风疹IGM
JL-FA-177
Rubeola Negative Plasma
风疹阴性血浆
JL-FA-178
Rubeola IgG
风疹IGG
JL-FA-179
Scleroderma (Scl-70) Pos
胶原沉着病,硬皮病,硬皮症 阳性
JL-FA-180
Scleroderma (Scl-70) Negative
硬皮病阴性
JL-FA-181
Sickle Cell Fresh Whole Blood
镰刀形红细胞新鲜全血
JL-FA-182
Smith (SM)
抗Smith抗体阳性血清(SLE的特征性抗体)
JL-FA-183
SMITH RNP
抗RNP抗体阳性血清(SLE的特征性抗体)
JL-FA-184
Smooth Muscle (ASMA)
抗平滑肌抗体阳性血清
JL-FA-185
Sjogren syndrome antigen A (SSA) Positive
舍格伦综合征或干燥综合征抗原A 阳性
JL-FA-186
Sjogren syndrome antigen B (SSB) Positive
舍格伦综合征抗原B 阳性
JL-FA-187
Sjogren syndrome antigen B (SSB) Negative
舍格伦综合征抗原B阴性
JL-FA-188
Streptolysin O Ab (ASO)
链球菌溶血素O抗体
JL-FA-189
Syphilis (RPR - Rapid Plasma Reagin) Positive Plasma
梅毒(梅毒-快速血浆反应)阳性血浆
JL-FA-190
Syphilis (RPR - Rapid Plasma Reagin) Negative Plasma
梅毒(梅毒-快速血浆反应)阴性血浆
JL-FA-191
Syphilis/ATA/T. pallidum IgG
梅毒ATA/T,苍白球IGG
JL-FA-192
Syphilis/ATA/T. pallidum IgM
梅毒ATA/T,苍白球IGM
JL-FA-193
Systemic Lupus Erythematosus (SLE) Positive
全身性红斑狼疮阳性
JL-FA-194
Systemic Lupus Erythematosus (SLE) Negative
全身性红斑狼疮阴性
JL-FA-195
TG/TPO Positive (Standard Titer 1,000 - 3000 IU/mL)
甲状腺球蛋白/甲状腺过氧化物酶阳性
JL-FA-196
TG/TPO Negative
甲状腺球蛋白/甲状腺过氧化物酶阴性
JL-FA-197
TTG (Tissue Transglutaminase)
组织转谷氨酰胺酶
JL-FA-198
TTG (Tissue Transglutaminase) IgA
组织转谷氨酰胺酶 IGA
JL-FA-199
ToRCH (Toxo, Rubella, CMV, HSV) Positive
优生优育(弓形虫,风疹,巨细胞,单胞)阳性
JL-FA-200
ToRCH (Toxo, Rubella, CMV, HSV) Negative
优生优育(弓形虫,风疹,巨细胞,单胞)阴性
JL-FA-201
Toxoplasmosis (Toxo)
弓形虫病
JL-FA-202
Toxoplasmosis (Toxo) IgG
弓形虫病IGG
JL-FA-203
Toxoplasmosis (Toxo) IgM
弓形虫病IGM
JL-FA-204
Thyroglobulin (TG) Positive Plasma
甲状腺球蛋白阳性血浆
JL-FA-205
Thyroglobulin (TG) Negative
甲状腺球蛋白阴性
JL-FA-206
Varicella-Zoster Virus (VZV) Negative
水痘-带状疱疹病毒阴性
JL-FA-207
Varicella-Zoster Virus (VZV) IgG
水痘-带状疱疹病毒IGG
JL-FA-208
Varicella-Zoster Virus (VZV) IgM
水痘-带状疱疹病毒IGM
JL-FA-209
West Nile Virus (WNV)
西尼罗河脑炎病毒
JL-FA-210
West Nile Virus (WNV) IgM
西尼罗河脑炎病毒IGM
美国Seracare衣原体IgG(Chlamydia IgG)
美国斯隆-凯特琳研究所等处的研究人员创建了一种多能干细胞基因组编辑平台:iCRISPR,这一平台能快速,高效的敲除干细胞中的基因,而且还能在干细胞分化过程中,进行阶段特异性的基因敲除,这将在人类疾病复杂病理研究中大放异彩。相关文章发表于2014年6月12日的《Cell Stem Cell》杂志上。
人体多能干细胞(hPSCs)不仅能被用于临床的再生研究应用中,而且也能作为解析复杂性状和特征的独特平台,阐明其背后的基因和分子途径。为了实现这一目的,科学家们开发了多种遗传操控方法,但是这些方法依然存在各种问题,我们需要快速,具有可操控性的生物学手段。
在这篇文章中,研究人员就利用CRISPR和TALEN,这两种备受关注的基因组编辑技术,研发出了一种人类多能干细胞基因组编辑平台。研究人员将这一平台称为iCRISPR。
iCRISPR能用于基因功能丧失研究中,快速,高效的敲除人体多能干细胞中的等位基因,也可以针对一些精确的疾病模型,通过特定的核苷酸变换,进行多能干细胞纯合体敲除。
通过进一步实验,研究人员验证了双重和三重基因敲除hPSC细胞系一步法的有效性,同时也证明了在多能干细胞分化过程中能进行阶段特异性诱导基因敲除,这对于发育生物学研究来说意义重大。
由此研究人员指出,iCRISPR平台尤其适合用于解析人类疾病研究中的复杂遗传相互作用,以及多效性基因功能,这将有助于进行人体多能干细胞高通量遗传分析。
除了这项研究之外,去年来自加州大学旧金山分校的研究人员提出了一个相似的名称:CRISPRi,他们发现当缺失核酸内切酶活性的Cas9与一种导向RNA共表达时候,会产生一种DNA识别复合物,这种复合物能特异性干扰转录延伸,RNA聚合酶结合,或转录因子结合。
由此研究人员研发出了这种CRISPRi系统,这一系统能有效抑制大肠杆菌中靶向基因的表达,并且不会出现脱靶效应。而且利用CRISPRi,还可以同时抑制多个靶基因,这种作用也是可逆。研究人员还证明,该系统也适用于哺乳动物细胞中的基因表达抑制。
加州大学圣迭戈分校(University of California, San Diego)医学院研究人员针对自闭症研究出一套比较新锐的理论,并对其进行了实际测试。研究结果显示,自闭症实际上是由异常的细胞通讯导致的,使用问世已逾百年的治疗嗜睡症的药物,可以恢复患有自闭症的老鼠体内的细胞活动,消除老鼠的神经失调症状。参与实验的老鼠年龄相当于人类30岁左右。相关研究成果在2014年6月17日的在线刊物《平移精神病学(Translational Psychiatry)》中发表。
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【公司名称】 广州健仑生物科技有限公司
【】 杨永汉
【】
【腾讯 】 2042552662
【公司地址】 广州清华科技园创新基地番禺石楼镇创启路63号二期2幢101-3室
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Researchers at the U.S.-based Sloan-Caitlin Institute have created iCRISPR, a pluripotent stem cell genomics editing platform that rapidly and efficiently knocks out genes in stem cells and helps them differentiate stem cells during stem cell differentiation, Performing stage-specific knockouts will shine in the complex pathology of human disease. The article appeared in the June 12, 2014 issue of Cell Stem Cell.
Not only can human pluripotent stem cells (hPSCs) be used in clinical regenerative research applications, but also as a unique platform for analyzing complex traits and traits, elucidating the underlying genetic and molecular pathways. To achieve this goal, scientists have developed a variety of genetic manipulation methods, but there are still a variety of problems with these methods, and we need fast, manipulative biological tools.
In this article, researchers developed a human pluripotent stem cell genome editing platform using two well-regarded genome editing technologies, CRISPR and TALEN. The researchers call this platform iCRISPR.
iCRISPR can be used in gene loss studies to rapidly and efficiently knock out alleles in pluripotent human pluripotent stem cells and to target specific models of disease through specific nucleotide transforms for pluripotent stem cell homozygous knocking except.
Through further experiments, the researchers validated the one-step efficacy of double and triple knockout hPSC cell lines, and also demonstrated that stage-specific induction of gene knockdown during pluripotent stem cell differentiation can be performed in developmental biology Meaningful.
As a result, the researchers noted that the iCRISPR platform is particularly well-suited for the analysis of complex genetic interactions in human disease research and pleiotropic gene functions that will facilitate high-throughput genetic analysis of human pluripotent stem cells.
In addition to the study, researchers from the University of California, San Francisco, last year proposed a similar name: CRISPRi, who found that a DNA lacking endonuclease co-expressed with a directing RNA produced a DNA Recognition complexes that specifically interfere with transcriptional elongation, RNA polymerase binding, or transcription factor binding.
As a result, the researchers developed the CRISPRi system, which effectively inhibits the expression of the targeted genes in E. coli and does not show off-target effects. And using CRISPRi, you can also inhibit multiple target genes, this effect is also reversible. The researchers also demonstrated that the system is also suitable for gene expression inhibition in mammalian cells.
Researchers at the University of California, San Diego Medical School developed a set of cutting-edge theories of autism and conducted practical tests. The results show that autism is actually caused by abnormal cell communication, the use of more than a century has come out of the treatment of narcolepsy drugs, can restore autism in mice with cell activity in vivo, to eliminate symptoms of neurological disorders in mice . The age of the mice involved in the experiment is about 30 years old. Relevant research results are published in the June 17, 2014 online translation "Translational Psychiatry."